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one additional patient receiving rosuvastatin 10 mg had an increase in ck of 5 uln, but this was not associated with muscle symptoms and not considered clinically important.

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children and adolescents 7 to 15 years of age with homozygous familial hypercholesterolemia were studied in a 6-week randomized, placebo-controlled, cross-over study with rosuvastatin 20 mg once daily followed by 12 weeks of open-label treatment see clinical studies 14.

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